Sunday 2 August 2015

Cryptococcus neoformans

BASIC CHARACTERISTICS: C. neoformans grows as a yeast (unicellular) and replicates by budding. It makes hyphae during mating, and eventually creates basidiospores at the end of the hyphae before producing spores. 
INFECTION : Infection with C. neoformans is termed cryptococosis. Most infections with C. neoformans occur in the lungs. However, fungal meningitis and encephalitis, especially as a secondary infection for AIDS patients, are often caused by C. neoformans, making it a particularly dangerous fungus. Infections with this fungus are rare in those with fully functioning immune systems. So, C. neoformans is sometimes referred to as an opportunistic fungus. Cryptococcus neoformanswas the first intracellular pathogen for which the non-lytic escape process termed vomocytosis was observed.

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